They are an organic compound whose functional group is RCONR'R 'type', CO being a carbonyl, N a nitrogen atom, and R, R 'and R' 'radicals or organic hydrogen atoms:

It can be considered as a derivative of a carboxylic acid by replacement of the -OH group of the acid group by a -NH2, -NHR or -NRR '(called amino group).

  • Amide functional group.

Formally also be considered derivatives of ammonia, a primary amine or a secondary amine by replacement of a hydrogen radical by an acid, resulting in a primary, secondary or tertiary amide, respectively.

Specifically they can be synthesized from a carboxylic acid and an amine:

Amide react.png

Amides all except the first of the series, are solid at room and their boiling points are high, higher than the temperature the corresponding acids. They have excellent solvent properties and are very weak bases. One of the main methods of obtaining these compounds consists of reacting ammonia (or primary or secondary amines) esters. Amides are common in nature, and one of the best known is urea, a diamide containing no hydrocarbons. Proteins and peptides are composed of amides. An example of long chain polyamide is nylon. Amides are also widely used in the pharmaceutical industry.

  • Polyamides

There polymers containing amide groups . Some are synthetic , such as nylon , but also found in nature in proteins , formed from amino acids , by reacting a carboxyl group of an amino acid with an amino group of another . In the amide group of proteins called peptide bond.

Nailon 6.png

nylon 6 

Certain polyamides are nylon type polyamide-6, polyamide-11, polyamide-12, polyamide-9,6, polyamide-6,9, polyamide-6,10 and polyamide-6,12. There may be mentioned as an example of nonlinear condensation products of dimerized acids with amines polyamides vegetable oils.

Proteins, such as silk, which replaced nylon, are also polyamides. These amide groups are very polar and can be joined together by hydrogen bridge links. Due to this and to chain nylon is so regular and symmetrical, nylons are often crystalline and excellent form fibers.

Examples of amides

Acrylamide is used in different applications, but is best known as probably carcinogenic and be present in many foods to be formed by natural processes to cooking.

They are a source of energy for the human body.

For example can be vitamins in the body or pain killers.

Importance and uses

Amides are common in nature and are found in substances such as amino acids, proteins, DNA and RNA, hormones and vitamins.

It is used by the body for excretion of ammonia (NH3)


Name Catalogue Bulletin/Spe. Sheet. Sec. Sheet GHS Sec. Sheet View
Name Catalogue Bulletin/Spe. Sheet. Sec. Sheet GHS Sec. Sheet View
Dimethyl Formamide


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